Adipocyte CLDN5 promotes thermogenesis and energy expenditure through regulation of IL10 expression

Adipocyte CLDN5 promotes thermogenesis and energy expenditure through regulation of IL10 expression

Abstract The claudin protein family plays key roles in maintaining normal structure and function of epithelial and endothelial tight junctions. While several prior studies have addressed the expression of claudin in adipocytes that do not form tight junctions, here we demonstrate that CLDN5 is selec...

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Main Authors: Ke Feng, Wenqin Wang, Xianlong Gao, Hejie Yan, Mengyuan Xu, Baozhen Fan, Qianfeng Jia, Chao Wang, Jian Yu, Yi Li, Qinfeng Xu, Yanan An, Peng Jiao, Mingxia Wang, Hui Sun, Feng Kong, Yongfeng Gong, Shengtian Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61371-3
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https://doi.org/10.1038/s41467-025-61371-3

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