Factors Influencing Nerinetide Effect on Clinical Outcome in Patients Without Alteplase Treatment in the ESCAPE-NA1 Trial

Factors Influencing Nerinetide Effect on Clinical Outcome in Patients Without Alteplase Treatment in the ESCAPE-NA1 Trial

Background and Purpose In the ESCAPE-NA1 (Efficacy and Safety of Nerinetide for the Treatment of Acute Ischaemic Stroke) trial, treatment with nerinetide was associated with improved outcomes in patients who did not receive intravenous alteplase. We compared the effect of nerinetide on clinical outc...

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Main Authors: Mayank Goyal, Bijoy K. Menon, Johanna Ospel, Mohammed Almekhlafi, Charlotte Zerna, Raul Nogueira, Ryan McTaggart, Andrew M. Demchuk, Alexandre Y. Poppe, Brian Buck, Kathy Heard, Manish Joshi, Diogo Haussen, Shawna Cutting, Shelagh B. Coutts, Daniel Roy, Jeremy L. Rempel, Thalia S. Field, Dar Dowlatshahi, Brian van Adel, Richard Swartz, Ruchir Shah, Eric Sauvageau, Volker Puetz, Frank L. Silver, Bruce Campbell, René Chapot, Michael Tymianski, Michael D. Hill, on Behalf of the ESCAPE-NA1 Investigators
Format: Article
Language:English
Published: Korean Stroke Society 2025-01-01
Series:Journal of Stroke
Subjects:
acute ischemic stroke
thrombectomy
neuroprotection
cerebroprotection
nerinetide
Online Access:http://j-stroke.org/upload/pdf/jos-2024-03139.pdf
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