Extracellular Vesicles from Regenerating Skeletal Muscle Mitigate Muscle Atrophy in an Amyotrophic Lateral Sclerosis Mouse Model

Extracellular Vesicles from Regenerating Skeletal Muscle Mitigate Muscle Atrophy in an Amyotrophic Lateral Sclerosis Mouse Model

Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor neuron degeneration and muscle atrophy, with no effective treatments available. Chronic inflammation, which impairs muscle regeneration and promotes proteolysis, is a key contributor to ALS-...

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Bibliographic Details
Main Authors: Jinghui Gao, Aria Sikal, Rachel Hankin, Yaochao Zheng, Elijah Sterling, Kenny Chan, Yao Yao
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
amyotrophic lateral sclerosis
regenerating skeletal muscle
extracellular vesicles
muscle atrophy
Online Access:https://www.mdpi.com/2073-4409/14/6/464
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