Identification of 1,400 metabolites as mediators of obesity in 473 gut microbiota taxa: a mediation Mendelian randomization study

ABSTRACT Obesity is a global health problem driven by genetic, endocrine, and environmental factors. Gut microbiota significantly influences obesity, yet causal relationships and underlying pathways remain elusive. The objective of the study was to investigate causal relationships between gut microb...

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Bibliographic Details
Main Authors: Xiaomin Li, Qike Wu, Shan-peng Liu
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01892-24
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