Power and sample size calculation for non-inferiority trials with treatment switching in intention-to-treat analysis comparing RMSTs
Abstract Background Difference in Restricted Mean Survival Time (DRMST) has attracted attention and is increasingly used in non-inferiority (NI) trials because of its superior power in detecting treatment effects compared to hazard ratio. However, when treatment switching (also known as crossover) o...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-025-02604-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|