Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac

Background: The aim of this study is to determine the impact of species and tissue differences on the glucuronidation of diclofenac in vitro. Method: Microsomes from different species (rat, monkey, mouse, dog, and human) and rat and human tissues (liver, intestine, and kidney) were used to assess th...

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Bibliographic Details
Main Authors: Eric Asare, Shalom Emmanuel, Ting Du, Huan Xie, Dong Liang, Song Gao
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/24/5867
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