Cooperation between Epstein-Barr virus immune evasion proteins spreads protection from CD8+ T cell recognition across all three phases of the lytic cycle.

CD8+ T cell responses to Epstein-Barr virus (EBV) lytic cycle expressed antigens display a hierarchy of immunodominance, in which responses to epitopes of immediate-early (IE) and some early (E) antigens are more frequently observed than responses to epitopes of late (L) expressed antigens. It has b...

Full description

Saved in:
Bibliographic Details
Main Authors: Laura L Quinn, Jianmin Zuo, Rachel J M Abbott, Claire Shannon-Lowe, Rosemary J Tierney, Andrew D Hislop, Martin Rowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004322
Tags: Add Tag
No Tags, Be the first to tag this record!