Dissecting spatio‐temporal protein networks driving human heart development and related disorders

Dissecting spatio‐temporal protein networks driving human heart development and related disorders

Abstract Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the underlying processes is very limited. Using heart morphogenesis as general model for dissecting the functional architecture of organ...

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Main Authors: Kasper Lage, Kjeld Møllgård, Steven Greenway, Hiroko Wakimoto, Joshua M Gorham, Christopher T Workman, Eske Bendsen, Niclas T Hansen, Olga Rigina, Francisco S Roque, Cornelia Wiese, Vincent M Christoffels, Amy E Roberts, Leslie B Smoot, William T Pu, Patricia K Donahoe, Niels Tommerup, Søren Brunak, Christine E Seidman, Jonathan G Seidman, Lars A Larsen
Format: Article
Language:English
Published: Springer Nature 2010-06-01
Series:Molecular Systems Biology
Subjects:
genetics
organ developmental networks
polygenic common disorders
proteomics
systems biology
Online Access:https://doi.org/10.1038/msb.2010.36
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https://doi.org/10.1038/msb.2010.36

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