In vitro effects of fluticasone propionate on IL-13 production by mitogen-stimulated lymphocytes

In vitro effects of fluticasone propionate on IL-13 production by mitogen-stimulated lymphocytes

Background: Corticosteroid administration produces multiple immunomodulatory effects, including down-regulation of cytokine production by CD4 T lymphocytes. Fluticasone propionate (FP) (Glaxo Smith&Kline, Greenford, UK), a highly lipophilic topical corticosteroid, has been shown to be safe and e...

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Main Authors: Gabriele Di Lorenzo, Maria Luisa Pacor, Maria Esposito Pellitteri, Sebastiano Gangemi, Patrizia Di Blasi, Giuseppina Candore, Alfredo Colombo, Domenico Lio, Calogero Caruso
Format: Article
Language:English
Published: Wiley 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09622935020138226
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Summary:Background: Corticosteroid administration produces multiple immunomodulatory effects, including down-regulation of cytokine production by CD4 T lymphocytes. Fluticasone propionate (FP) (Glaxo Smith&Kline, Greenford, UK), a highly lipophilic topical corticosteroid, has been shown to be safe and effective in the treatment of asthma and of both seasonal and perennial rhinitis.
ISSN:0962-9351
1466-1861

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