Genomic variation in Pseudomonas aeruginosa clinical respiratory isolates with de novo resistance to a bacteriophage cocktail

Genomic variation in Pseudomonas aeruginosa clinical respiratory isolates with de novo resistance to a bacteriophage cocktail

ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that can cause sinus infections and pneumonia in cystic fibrosis (CF) patients. Bacteriophage therapy is being investigated as a treatment for antibiotic-resistant P. aeruginosa infections. Although virulent bacteriophages have shown promi...

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Bibliographic Details
Main Authors: Stephanie A. Fong, George Bouras, Ghais Houtak, Roshan Nepal, Sholeh Feizi, Sandra Morales, Alkis J. Psaltis, Peter-John Wormald, Sarah Vreugde
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
bacteriophage
Pseudomonas aeruginosa
cystic fibrosis
multidrug resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02149-24
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https://journals.asm.org/doi/10.1128/spectrum.02149-24

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