Long-term effects of BCG vaccination on telomere length and telomerase activity

Long-term effects of BCG vaccination on telomere length and telomerase activity

Summary: This study explores the effects of Bacillus Calmette-Guérin (BCG) vaccination on telomere maintenance, an aging-related process, in immune cells. While BCG reduces systemic inflammation and enhances innate immune responsiveness by inducing trained immunity, its effects on other immune aging...

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Bibliographic Details
Main Authors: Ozlem Bulut, Valerie A.C.M. Koeken, Simone J.C.F.M. Moorlag, Charlotte J. de Bree, Vera P. Mourits, Gizem Kilic, Priya A. Debisarun, Marijke P.A. Baltissen, Joost H.A. Martens, Jorge Domínguez-Andrés, Leo A.B. Joosten, Mihai G. Netea
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Immunology
Age
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225014208
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http://www.sciencedirect.com/science/article/pii/S2589004225014208

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