Folic Acid Mitigates Sertraline-Induced Liver Damage in Adult Female Albino Rats During Pregnancy and Postpartum: A Biochemical and Histological Study

Folic Acid Mitigates Sertraline-Induced Liver Damage in Adult Female Albino Rats During Pregnancy and Postpartum: A Biochemical and Histological Study

<i>Background and Objectives:</i> Sertraline is a selective serotonin reuptake inhibitor (SSRI) that is frequently prescribed during pregnancy to treat mood disorders. Studies indicate that chronic use of sertraline is associated with elevated liver enzymes, oxidative stress, and histolo...

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Main Authors: Ayman A. Refai, Mohammad I. Jumaa, Einas M. Yousef, Ala M. Aljehani, Rana Ahmed Alduraywish, Mohamed R. Elkabary, Safaa M. Hanafy, Hanan S. Seleem, Eman S. El-Roghy
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Medicina
Subjects:
apoptosis
caspase 3
folic acid
hepatotoxicity
pregnancy
sertraline
Online Access:https://www.mdpi.com/1648-9144/61/4/751
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