Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents

Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents

In the present study novel heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) (1, 2, 3, 4a-e and 5a-e) were designed and synthesized and investigated for their antimicrobial (against selected bacteria and fungi) and anticancer potential. The molecules 4e and 5e...

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Bibliographic Details
Main Authors: Richie R Bhandare, Chandrashekar S.Munikrishnappa, G.V. Suresh Kumar, Sathish Kumar Konidala, Dilep Kumar Sigalapalli, Yogesh Vaishnav, Sampath Chinnam, Haya Yasin, Ahmed A. Al-karmalawy, Afzal B. Shaik
Format: Article
Language:English
Published: Springer 2022-05-01
Series:Journal of Saudi Chemical Society
Subjects:
Heterocyclic tetrads
Cancer
Microbial infections
Docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610322000291
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