How Can the Microbiologist Help in Diagnosing Neonatal Sepsis?
Neonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early-onset neonatal sepsis—EONS) or later (late-onset neonatal sepsis—LONS). These definitions have contributed greatly to diagnosis and treatment by identifying which microo...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2012/120139 |
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| _version_ | 1832565188655579136 |
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| author | Michela Paolucci Maria Paola Landini Vittorio Sambri |
| author_facet | Michela Paolucci Maria Paola Landini Vittorio Sambri |
| author_sort | Michela Paolucci |
| collection | DOAJ |
| description | Neonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early-onset neonatal sepsis—EONS) or later (late-onset neonatal sepsis—LONS). These definitions have contributed greatly to diagnosis and treatment by identifying which microorganisms are likely to be responsible for sepsis during these periods and the expected outcomes of infection. This paper focuses on the tools that microbiologist can offer to diagnose and eventually prevent neonatal sepsis. Here, we discuss the advantages and limitation of the blood culture, the actual gold standard for sepsis diagnosis. In addition, we examine the utility of molecular techniques in the diagnosis and management of neonatal sepsis. |
| format | Article |
| id | doaj-art-a8acc8db83184762a7a478422478fbff |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-a8acc8db83184762a7a478422478fbff2025-02-03T01:09:03ZengWileyInternational Journal of Pediatrics1687-97401687-97592012-01-01201210.1155/2012/120139120139How Can the Microbiologist Help in Diagnosing Neonatal Sepsis?Michela Paolucci0Maria Paola Landini1Vittorio Sambri2Unit of Microbiology, Department of Haematology and Oncology “L. e A. Seràgnoli”, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyUnit of Microbiology, Department of Haematology and Oncology “L. e A. Seràgnoli”, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyUnit of Microbiology, Department of Haematology and Oncology “L. e A. Seràgnoli”, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyNeonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early-onset neonatal sepsis—EONS) or later (late-onset neonatal sepsis—LONS). These definitions have contributed greatly to diagnosis and treatment by identifying which microorganisms are likely to be responsible for sepsis during these periods and the expected outcomes of infection. This paper focuses on the tools that microbiologist can offer to diagnose and eventually prevent neonatal sepsis. Here, we discuss the advantages and limitation of the blood culture, the actual gold standard for sepsis diagnosis. In addition, we examine the utility of molecular techniques in the diagnosis and management of neonatal sepsis.http://dx.doi.org/10.1155/2012/120139 |
| spellingShingle | Michela Paolucci Maria Paola Landini Vittorio Sambri How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? International Journal of Pediatrics |
| title | How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? |
| title_full | How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? |
| title_fullStr | How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? |
| title_full_unstemmed | How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? |
| title_short | How Can the Microbiologist Help in Diagnosing Neonatal Sepsis? |
| title_sort | how can the microbiologist help in diagnosing neonatal sepsis |
| url | http://dx.doi.org/10.1155/2012/120139 |
| work_keys_str_mv | AT michelapaolucci howcanthemicrobiologisthelpindiagnosingneonatalsepsis AT mariapaolalandini howcanthemicrobiologisthelpindiagnosingneonatalsepsis AT vittoriosambri howcanthemicrobiologisthelpindiagnosingneonatalsepsis |