Inhibition of fatty acid binding protein suppresses pancreatic cancer progression and metastasis

Inhibition of fatty acid binding protein suppresses pancreatic cancer progression and metastasis

Abstract Obesity is a known risk factor for Pancreatic ductal adenocarcinoma (PDAC). Fatty acid binding protein 4 (FABP4) is higher in plasma of obese patients, and linked to the progression of obesity-related cancers. To provide insights into the role of FABP4 in PDAC progression and determine the...

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Bibliographic Details
Main Authors: Shuhei Shinoda, Naohiko Nakamura, Kazuho Inoko, Mizuho Sato-Dahlman, Steven Carmella, Stephen Hecht, David A Bernlohr, Sayeed Ikramuddin, Masato Yamamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Pancreatic ductal adenocarcinoma
Fatty acid binding protein 4
Metastasis
Obesity
Online Access:https://doi.org/10.1038/s41598-025-11271-9
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https://doi.org/10.1038/s41598-025-11271-9

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