Cirrhosis Caused by Nilotinib in Dose-Dependent Hepatotoxicity: Role of Gamma-Glutamyl Transferase in Management

We report nilotinib hepatotoxicity in a patient with chronic myeloid leukemia (CML) who presented with isolated elevations of gamma-glutamyl transferase (GGT). Cirrhosis was confirmed by clinical, radiologic, and histologic findings. Therapy for CML was continued, guided by monitoring BCR-ABL1 level...

Full description

Saved in:
Bibliographic Details
Main Authors: Jacob Korula, Edward Reece, Merrill Shum, Sanja Krajisnik, Carlos Echeverria, Paul O'Connor, Conrad Lu
Format: Article
Language:English
Published: American College of Physicians 2025-01-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0294
Tags: Add Tag
No Tags, Be the first to tag this record!