Activation of cannabinoid type 2 (CB2) receptors promotes the maintenance of redox homeostasis and protects against oxidative distress in the Neotropical freshwater fish matrinxã Brycon amazonicus (Characiformes: Bryconidae)

Activation of cannabinoid type 2 (CB2) receptors promotes the maintenance of redox homeostasis and protects against oxidative distress in the Neotropical freshwater fish matrinxã Brycon amazonicus (Characiformes: Bryconidae)

Abstract Recent evidence indicates significant interaction of cannabinoid receptors (CB1 and CB2) with redox mechanisms. This study investigated the effects of the cannabinoid agonists WIN 55,212-2 (CB1+CB2) and HU-308 (CB2) on oxidative biomarkers in the liver and heart of the fish Brycon amazonicu...

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Bibliographic Details
Main Authors: Suzana Luisa Alves Fernandes, Yan Costa Gonçalves, Francisco Tadeu Rantin, Ana Lúcia Kalinin, Diana Amaral Monteiro
Format: Article
Language:English
Published: Sociedade Brasileira de Ictiologia 2024-11-01
Series:Neotropical Ichthyology
Subjects:
Antioxidant defense system
Cannabinoid agonists
Heart
Liver
Oxidative damage
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-62252024000400202&lng=en&tlng=en
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-62252024000400202&lng=en&tlng=en

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