PROCR diminishes the efficacy of radiation by impairing T-cell-mediated antitumour immunity

Abstract T cell dependent anti-tumour immunity reprogrammed by radiotherapy is critical for its efficacy. However, the mechanisms by which tumour cells hinder this process remain poorly understood. Here, we show that tumour cells expressing protein C receptor (PROCR) dampen antitumour immunity by pr...

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Bibliographic Details
Main Authors: Weipeng Chen, Chuqing Zhang, Zhe Li, Zhimin Xu, Cong Ding, Jiawei Wu, Hanmiao Wei, Zhenji Deng, Tingxiang He, Liufen Long, Yanping Mao, Jun Ma, Xiaoyu Liang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62558-4
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