APOE Drives Glioma Progression by Modulating CCL5/CCR5 Signaling in the Tumor Microenvironment and Inducing M2 Macrophage Polarization
Background: Tumor-associated macrophages (TAMs) are pivotal in shaping the tumor microenvironment (TME) during cancer progression. Emerging evidence indicates that dysregulation of key signaling pathways in cancer cells drives the secretion of various cytokines, modulating TAMs function. This study...
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| Main Authors: | Wei Huang, Weimin Li, Xingyu Chen, Chengwei Xiang, Ke Luo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Immunobiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0171298525000294 |
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