Comparative immunological study of Plasmodium knowlesi infections in humans and macaques: insights into cytokine dynamics

Comparative immunological study of Plasmodium knowlesi infections in humans and macaques: insights into cytokine dynamics

Abstract Background Plasmodium knowlesi, a simian malaria parasite endemic to Southeast Asia, is transmitted from macaques to humans via mosquitoes and has seen a surge due to human encroachment into macaque habitats. While the primary host, Macaca fascicularis, can regulate P. knowlesi and alleviat...

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Main Authors: Mohammad Faruq Abd Rachman Isnadi, Yean Kong Yong, Matthew J. Grigg, Symphorosa Sipangkui, Ping-Chin Lee, Nor Afizah Nuin, Angelica Fiona Tan, Paul Molius, Augustine Tuuga, Jum Rafiah Abd Sukor, Giri Rajahram, Sylvia Daim, Tock H. Chua
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Malaria Journal
Online Access:https://doi.org/10.1186/s12936-025-05478-4
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https://doi.org/10.1186/s12936-025-05478-4

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