O-prenylchalcones inhibit cell proliferation and activate apoptosis by inducing mitochondrial dysfunction in gastric cancer cells

Abstract Purpose Treatments for gastric cancer are based on neoadjuvant chemoradiotherapy and molecular-targeted therapies, but these modalities lead to poor outcomes. Therefore, identifying and testing novel drugs with potential anticancer properties is highly important. Chalcones are favoured mole...

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Bibliographic Details
Main Authors: José C. Espinoza-Hicks, Yarely M. Salinas-Vera, Javier Camarillo-Cisneros, Alejandro A. Camacho-Dávila, Jessica L. Hernández-Rivera, Nadia Flores-Huerta, Eloisa Ibarra-Sierra, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Ángeles C. Tecalco-Cruz, César López-Camarillo
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-03130-w
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