Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission regions of Uganda

Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission regions of Uganda

Abstract Background Artemisinin-based combination therapy (ACT) is currently recommended for treatment of uncomplicated malaria. However, the emergence and spread of partial artemisinin resistance threatens their effectiveness for malaria treatment in sub-Saharan Africa where the burden of malaria i...

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Main Authors: Bosco B. Agaba, Jye Travis, David Smith, Simon P. Rugera, Maria G. Zalwango, Jimmy Opigo, Charles Katureebe, Ruth Mpirirwe, Dembo Bakary, Martin Antonio, Beshir Khalid, Joseph Ngonzi, Moses R. Kamya, Pontiano Kaleebu, Peter Piot, Qin Cheng
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Malaria Journal
Subjects:
Genomic surveillance
Plasmodium falciparum
pfk13 mutations
Emergence
Artemisinin resistance
Online Access:https://doi.org/10.1186/s12936-024-05158-9
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https://doi.org/10.1186/s12936-024-05158-9

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