Progress in pharmacogenetic studies on effect on tacrolimus concentrations

The pharmacokinetic and pharmacodynamic parameters of tacrolimus have big individual differences,and the drug has a narrow treatment window.These are main causes leading to rejection and toxic reactions,and hereditary factors are one of main causes for individual difference of tacrolimus efficacy.In...

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Bibliographic Details
Main Authors: YANG Shuang, WANG Li-ning
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2020-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57906954&Fpath=home&index=0
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