Cell-Based Relative Potency of a Respiratory Syncytial Virus mRNA Vaccine Correlates with In Vivo Immunogenicity

Cell-Based Relative Potency of a Respiratory Syncytial Virus mRNA Vaccine Correlates with In Vivo Immunogenicity

<b>Background/Objectives:</b> Potency is a critical quality attribute for vaccine development as well as clinical drug product (DP) lot release and stability testing. Animal studies have the potential to offer conclusive insights about the potency of vaccines by demonstrating technical r...

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Main Authors: Katrina Feller, Hesham Nawar, Liping Song, Amanda Abrams, Liang Shang, Ashley Gruber, Tatyana Yun, Hualin Helen Li
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Vaccines
Subjects:
mRNA vaccine
potency assay
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/13/3/326
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