Glucocorticoid receptor-targeting antagomirs alleviates AFB1-induced hepatotoxicity in mice

Aflatoxin B1 (AFB1) exhibits hepatotoxic properties in both humans and animals. Contradictory findings regarding corticosterone suggest that it may either aggravate AFB1 toxicity or reduce its Lethal Dose 50 % (LD50), potentially through the role of the glucocorticoid receptor (GR). Additionally, mi...

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Bibliographic Details
Main Authors: Mindie Zhao, Yulan Zhao, Jie Liu, Huimin Chen, Ruqian Zhao
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325002714
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