Integrated multi-omics profiling characterizes the crucial role of human dental epithelium during tooth development

Integrated multi-omics profiling characterizes the crucial role of human dental epithelium during tooth development

Summary: The development of early human tooth primordia is not well understood. Here, we linked single-cell RNA sequencing, spatial transcriptomics, and secretome analysis to characterize human fetal tooth development over time. A spatiotemporal atlas of human tooth development at multiple levels wa...

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Main Authors: Ran Zhang, Zongshan Shen, Zhenni Zhao, Xiuge Gu, Tianxing Yan, Wei Wei, Chuan Wu, Jinxuan Xia, Yuanyuan Zhang, Suwen Chen, Linsha Ma, Dong Zhang, Xiaoshan Wu, Paul T. Sharpe, Songlin Wang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Cell Reports
Subjects:
CP: Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725002086
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