Quantitative detection of T315I mutations of BCR::ABL1 using digital droplet polymerase chain reaction

Background: T315I mutations of the BCR::ABL1 gene lead to resistance to tyrosine kinase inhibitors (TKIs). This study evaluated the performance of digital droplet polymerase chain reaction (ddPCR) in quantifying T315I mutations and their frequency in Philadelphia chromosome (Ph) positive hematologic...

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Bibliographic Details
Main Authors: Huijun Mu, Jian Zou, Haiping Zhang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Hematology, Transfusion and Cell Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924000300
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