Human-machine co-adaptation to automated insulin delivery: a randomised clinical trial using digital twin technology

Abstract Most automated insulin delivery (AID) algorithms do not adapt to the changing physiology of their users, and none provide interactive means for user adaptation to the actions of AID. This randomised clinical trial tested human-machine co-adaptation to AID using new ‘digital twin’ replay sim...

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Main Authors: Boris P. Kovatchev, Patricio Colmegna, Jacopo Pavan, Jenny L. Diaz Castañeda, Maria F. Villa-Tamayo, Chaitanya L. K. Koravi, Giulio Santini, Carlene Alix, Meaghan Stumpf, Sue A. Brown
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01679-y
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