Regulatory mechanism and prognostic value of sex hormone pathways connected with metabolism and immune signaling in clear cell renal cell carcinoma

Abstract Clear cell renal cell carcinoma (ccRCC) represents a major subtype of kidney cancer with variable prognosis. A comprehensive understanding of sex hormone-related pathways could potentially refine the prediction of patient outcomes in ccRCC. Patients from TCGA-KIRC (n = 528) and GSE22541 (n ...

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Bibliographic Details
Main Authors: Xinyu Geng, Jiahao Shan, Yu Dai, Ziwei Liu, Simin Min, Shuo Zhao, Zhengyuan Zhang, Kai Shi, Duobing Zhang, Tuo Ji, Baoyuan Chang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97163-4
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