Significant association of hyperandrogenism and insulin resistance with the epigenetic alterations in PPARG1 gene in granulosa cells of PCOS females

Abstract Background Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine and metabolic disorders, affecting approximately 15% of females. This syndrome is characterized by its remarkable heterogeneity, and epigenetic factors may contribute to its development. Since the PPARG gene...

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Bibliographic Details
Main Authors: Zahra Dashti, Vahid Razban, Jafar Fallahi, Mohammad ebrahim Parsanezhad, Shayesteh Mehdinejadiani, Nasrin Ghasemi
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Egyptian Journal of Medical Human Genetics
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Online Access:https://doi.org/10.1186/s43042-025-00731-6
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