Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening of fucoidan analogues, its synthesis, characterization, and potential in-vitro anti-dengue activity
Abstract Dengue virus (DENV) disease, a life-threatening disease, is caused by DENV. In this research, a total of 24 analogues were designed by targeting the 2, hydroxyl and 2, methyl groups of parent fucoidan, and their interactions with DENV were investigated for their ability to suppress DENV thr...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
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| Series: | Discover Applied Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s42452-025-06867-9 |
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