Intestinal flora metabolites indole-3-butyric acid and disodium succinate promote IncI2 mcr-1-carrying plasmid transfer

Intestinal flora metabolites indole-3-butyric acid and disodium succinate promote IncI2 mcr-1-carrying plasmid transfer

IntroductionPlasmid-driven horizontal transfer of resistance genes in bacterial communities is a major factor in the spread of resistance worldwide. The gut microbiome, teeming with billions of microorganisms, serves as a reservoir for resistance genes. The metabolites of gut microorganisms strongly...

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Bibliographic Details
Main Authors: Jialiang Xu, Mengke Zhang, Yi Yan, Zhe Li, Xin Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
mcr-1-carrying plasmid
intestinal flora metabolite
conjugation
IncI2
IBA
DS
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1564810/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1564810/full

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