ScRNA-seq reveals novel immune-suppressive T cells and investigates CMV-TCR-T cells cytotoxicity against GBM

ScRNA-seq reveals novel immune-suppressive T cells and investigates CMV-TCR-T cells cytotoxicity against GBM

Background Glioblastoma (GBM) is a fatal primary brain malignancy in adults. Previous studies have shown that cytomegalovirus (CMV) is a risk factor for tumorigenesis and aggressiveness for glioblastoma. However, little is known about how CMV infection affects immune cells in the tumor microenvironm...

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Main Authors: Wei Gao, Qing Liu, Xiang Lin, Yiming Zhao, Minghua Wu, Shuai Chen, Peng Du, Meng Huang, Cheng Huang, Xiangyu Wang, Xinmiao Long, Zuping Zhang, Yuzhe Li, Kun Deng, Xiaoling She, Minfu Zhang, Shiyi Wang, Yinfei Du
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/4/e008967.full
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https://jitc.bmj.com/content/12/4/e008967.full

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