Gene-based sequencing identifies lipid-influencing variants with ethnicity-specific effects in African Americans.

Gene-based sequencing identifies lipid-influencing variants with ethnicity-specific effects in African Americans.

Although a considerable proportion of serum lipids loci identified in European ancestry individuals (EA) replicate in African Americans (AA), interethnic differences in the distribution of serum lipids suggest that some genetic determinants differ by ethnicity. We conducted a comprehensive evaluatio...

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Main Authors: Amy R Bentley, Guanjie Chen, Daniel Shriner, Ayo P Doumatey, Jie Zhou, Hanxia Huang, James C Mullikin, Robert W Blakesley, Nancy F Hansen, Gerard G Bouffard, Praveen F Cherukuri, Baishali Maskeri, Alice C Young, Adebowale Adeyemo, Charles N Rotimi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1004190
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https://doi.org/10.1371/journal.pgen.1004190

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