Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake
Abstract The serotonin 2C receptor regulates food uptake, and its activity is regulated by alternative pre‐mRNA splicing. Alternative exon skipping is predicted to generate a truncated receptor protein isoform, whose existence was confirmed with a new antiserum. The truncated receptor sequesters the...
Saved in:
| Main Authors: | Zhaiyi Zhang, Manli Shen, Paul J Gresch, Masoud Ghamari‐Langroudi, Alexander G Rabchevsky, Ronald B Emeson, Stefan Stamm |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2016-07-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201506030 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Alternative splicing in stem cells and development: research progress and emerging technologies
by: Yan Jin, et al.
Published: (2025-06-01) -
Parvovirus RNA Processing: Compact Genomic Organization and Unique Alternative mRNA Processing Mechanisms
by: Lisa K. Uhl, et al.
Published: (2025-07-01) -
Predominant contribution of cis‐regulatory divergence in the evolution of mouse alternative splicing
by: Qingsong Gao, et al.
Published: (2015-07-01) -
The landscape of human mutually exclusive splicing
by: Klas Hatje, et al.
Published: (2017-12-01) -
Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma
by: Siyi He, et al.
Published: (2025-03-01)