SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells.

Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related modifier (SUMO) to this kinase impacts on multiple cellular functions, such as pr...

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Main Authors: Marcos Francia, Martin Stortz, Camila Vazquez Echegaray, Camila Oses, Paula Verneri, María Victoria Petrone, Ayelen Toro, Ariel Waisman, Santiago Miriuka, María Soledad Cosentino, Valeria Levi, Alejandra Guberman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254447&type=printable
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