Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer

Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer

This study investigates the variability among patients with non-small cell lung cancer (NSCLC) in their responses to immune checkpoint inhibitors (ICIs). Recognizing that patients with advanced-stage NSCLC rarely qualify for surgical interventions, it becomes crucial to identify biomarkers that infl...

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Bibliographic Details
Main Authors: Nayoung Kim, Sehhoon Park, Areum Jo, Hye Hyeon Eum, Hong Kwan Kim, Kyungjong Lee, Jong Ho Cho, Bo Mi Ku, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Jung-Il Lee, Jung Won Choi, Dasom Jeong, Minsu Na, Huiram Kang, Jeong Yeon Kim, Jung Kyoon Choi, Hae-Ock Lee, Myung-Ju Ahn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
Subjects:
non-small cell lung cancer
immune checkpoint therapy
late-stage biopsy
single-cell RNA sequencing
response signature
Online Access:https://elifesciences.org/articles/98366
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https://elifesciences.org/articles/98366

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