Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital

Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital

Metabolic dysfunction-associated Steatohepatitis (MASH), is a prominent cause for liver cirrhosis. MASH-cirrhosis is responsible for liver complications and there is no specific treatment. To develop new therapeutic approaches, animal models are needed. The aim of this study was to develop a fast an...

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Bibliographic Details
Main Authors: Nico Kraus, Frank Erhard Uschner, Magnus Moeslein, Robert Schierwagen, Wenyi Gu, Maximilian Joseph Brol, Eike Fürst, Inga Grünewald, Sophie Lotersztajn, Pierre-Emmanuel Rautou, Marta Duran-Güell, Roger Flores Costa, Joan Clària, Jonel Trebicka, Sabine Klein
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
metabolic dysfunction-associated steatohepatitis (MASH)
carbon tetrachloride (CCl<sub>4</sub>)
high-fat and high-cholesterol Western diet (WD)
phenobarbital (PB)
long-term (LT)
short-term (ST)
Online Access:https://www.mdpi.com/2073-4409/13/20/1707
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