Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer.

Neoadjuvant chemotherapy induces expression levels of breast cancer resistance protein that predict disease-free survival in breast cancer.

Three main xenobiotic efflux pumps have been implicated in modulating breast cancer chemotherapy responses. These are P-glycoprotein (Pgp), Multidrug Resistance-associated Protein 1 (MRP1), and Breast Cancer Resistance Protein (BCRP). We investigated expression of these proteins in breast cancers be...

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Bibliographic Details
Main Authors: Baek Kim, Hiba Fatayer, Andrew M Hanby, Kieran Horgan, Sarah L Perry, Elizabeth M A Valleley, Eldo T Verghese, Bethany J Williams, James L Thorne, Thomas A Hughes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0062766&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0062766&type=printable

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