A gene‐centered C. elegans protein–DNA interaction network provides a framework for functional predictions

A gene‐centered C. elegans protein–DNA interaction network provides a framework for functional predictions

Abstract Transcription factors (TFs) play a central role in controlling spatiotemporal gene expression and the response to environmental cues. A comprehensive understanding of gene regulation requires integrating physical protein–DNA interactions (PDIs) with TF regulatory activity, expression patter...

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Bibliographic Details
Main Authors: Juan I Fuxman Bass, Carles Pons, Lucie Kozlowski, John S Reece‐Hoyes, Shaleen Shrestha, Amy D Holdorf, Akihiro Mori, Chad L Myers, Albertha JM Walhout
Format: Article
Language:English
Published: Springer Nature 2016-10-01
Series:Molecular Systems Biology
Subjects:
C. elegans
gene regulation
protein–DNA interaction network
transcription factors
yeast one‐hybrid assays
Online Access:https://doi.org/10.15252/msb.20167131
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https://doi.org/10.15252/msb.20167131

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