Causal effect of three autoimmune diseases on brain functional networks and cerebrospinal fluid metabolites to underlie the pathogenesis of autoimmune psychosis: a two-sample mendelian randomization analysis

Abstract Background Autoimmune diseases such as Systemic Lupus Erythematosus (SLE), Sjögren’s Syndrome (SS), and Hashimoto’s Thyroiditis (HT) frequently exhibit neuropsychiatric manifestations, including cognitive impairment, depression, anxiety, and so on, yet the exact pathogenesis underlying this...

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Bibliographic Details
Main Authors: Weiman Shi, Min Chen, Rongai Wang, Chengping Wen, Lin Huang, Qiao Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06113-1
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