Structure-based design and synthesis of (E)-l-(s-pheny1)-N-(4-(2,2,4-trimethy1–2,3-dihydro-lH-benzo[b][l,4]diazepin-l-yl)phenyl)methanimine motifs as antimicrobial and anti-tubercular agents

Structure-based design and synthesis of (E)-l-(s-pheny1)-N-(4-(2,2,4-trimethy1–2,3-dihydro-lH-benzo[b][l,4]diazepin-l-yl)phenyl)methanimine motifs as antimicrobial and anti-tubercular agents

Benzodiazepines' chemistry and synthesis as heterocyclic compounds have recently attracted a lot of attention, due to their extensive biological diversity in drug design and potential for usage in agrochemicals. Eco-friendly and highly efficient method was herein reported for the synthesis of a...

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Bibliographic Details
Main Authors: Olayinka O. Ajani, Mfonobong L. Ekpene, Gbolahan O. Oduselu, Olayinka O. Tolu-Bolaji, Oluwaseun Ejilude
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Scientific African
Subjects:
Benzodiazepines
Drug design
Microwave irradiation
Synthesis
Microbial growth inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227624004009
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