Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential

Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential

Abstract Red blood cells and platelets derive from bi-potential bone marrow megakaryocyte-erythroid progenitors, but their study is constrained by cell scarcity and limited experimental systems. Here we show that conditional expression of a virally transduced, regulated form of Hoxa7 enables expansi...

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Main Authors: Ruiqiong Wu, Faraz Salehi, Vanessa Redecke, Zhijun Ma, Marco Marchetti, David Finkelstein, Peng Xu, Yong Cheng, Kimberly A. Queisser, Aaron C. Petrey, Conroy O. Field, Hyun Sook Ahn, Mortimer Poncz, Mitchell J. Weiss, Hans Häcker
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62668-z
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https://doi.org/10.1038/s41467-025-62668-z

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