Multiscale Dissection of Spatial Heterogeneity by Integrating Multi‐Slice Spatial and Single‐Cell Transcriptomics

Abstract The spatial structure of cells is highly organized at multiscale levels from global spatial domains to local cell type heterogeneity. Existing methods for analyzing spatially resolved transcriptomics (SRT) are separately designed for either domain alignment across multiple slices or deconvo...

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Bibliographic Details
Main Authors: Yuqi Chen, Caiwei Zhen, Yuanyuan Mo, Juan Liu, Lihua Zhang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202413124
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