Hardware acceleration of the novel two dimensional Burrows‐Wheeler Aligner algorithm with maximal exact matches seed extension kernel

Hardware acceleration of the novel two dimensional Burrows‐Wheeler Aligner algorithm with maximal exact matches seed extension kernel

Abstract Next‐generation sequencing techniques have dramatically increased the amount of genomic data being sequenced, which calls for the acceleration of the alignment algorithms. This article proposes an FPGA‐based accelerated implementation of the seed extension kernel of the Burrows–Wheeler alig...

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Bibliographic Details
Main Authors: Mahdi Taheri, Mohammad Saeed Ansari, Sebastian Magierowski, Ali Mahani
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:IET Circuits, Devices and Systems
Subjects:
approximation theory
error compensation
field programmable gate arrays
matrix algebra
systolic arrays
hardware accelerators
Online Access:https://doi.org/10.1049/cds2.12005
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https://doi.org/10.1049/cds2.12005

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