Global motions of the nuclear pore complex: insights from elastic network models.

The nuclear pore complex (NPC) is the gate to the nucleus. Recent determination of the configuration of proteins in the yeast NPC at approximately 5 nm resolution permits us to study the NPC global dynamics using coarse-grained structural models. We investigate these large-scale motions by using an...

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Bibliographic Details
Main Authors: Timothy R Lezon, Andrej Sali, Ivet Bahar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000496&type=printable
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