Expression of recombination antimicrobial protein PIL22-PBD-2 in Pichia pastoris and verification of its biological function in vitro

Expression of recombination antimicrobial protein PIL22-PBD-2 in Pichia pastoris and verification of its biological function in vitro

Abstract Finding suitable alternatives to antibiotics as feed additives is challenging for the livestock industry. Porcine beta-defensin 2 (PBD-2) is an endogenous antimicrobial peptide produced by pigs. Due to its broad-spectrum antibacterial activity against various microorganisms and its low tend...

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Bibliographic Details
Main Authors: Xian Li, Pengfei Qiu, Menglong Yue, Ying Zhang, Congshang Lei, Jingyu Wang, Xiwen Chen, Xuefeng Qi
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Veterinary Research
Subjects:
Antibiotic-resistant
recombinant antimicrobial protein
eukaryotic expression
intestinal repair
feed additive
Online Access:https://doi.org/10.1186/s13567-024-01428-1
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https://doi.org/10.1186/s13567-024-01428-1

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