Report of two patients in whom comparisons of the somatic mutation profile were useful for the diagnosis of metastatic tumors

Report of two patients in whom comparisons of the somatic mutation profile were useful for the diagnosis of metastatic tumors

Abstract Background When a patient has multiple tumors in different organs, it is very important to identify whether the tumors are multiple cancers or metastasis from one tumor in order to establish an optimal treatment strategy. However, it is difficult to obtain an accurate diagnosis from convent...

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Main Authors: Kenichiro Furukawa, Keiichi Hatakeyama, Masanori Terashima, Keiichi Fujiya, Yutaka Tanizawa, Etsuro Bando, Takashi Sugino, Kenichi Urakami, Tateaki Naito, Hiroyasu Kagawa, Ken Yamaguchi
Format: Article
Language:English
Published: Japan Surgical Society 2022-12-01
Series:Surgical Case Reports
Subjects:
Diagnosis of a metastatic tumor
Somatic mutation comparison
Next-generation sequencing
Gene mutational signature
Panel sequencing
Online Access:https://doi.org/10.1186/s40792-022-01566-8
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https://doi.org/10.1186/s40792-022-01566-8

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