Conditional immortalization of olfactory ensheathing cells for intelligently regulating their proliferation state
Abstract Olfactory ensheathing cells (OECs) are among the most promising cell types for the treatment of spinal cord injury (SCI) and other neural traumas. However, primary OECs cultured in vitro are constrained by their inherent “Hayflick limit,” resulting in poor proliferative and passaging capaci...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-15144-z |
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