C-terminal amide-bearing proteins: emerging targets for protein homeostasis in health and disease

This study highlights the role of C-terminal amide-bearing proteins (CTAPs) in protein homeostasis. Researchers discovered that CTAPs, formed under oxidative stress, are selectively recognized and degraded by the E3 ubiquitin ligase FBXO31 to maintain cellular health. Mutations in FBXO31, such as D3...

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Bibliographic Details
Main Authors: Chen Zhang, Ruichen Zang, Yanlan Yu, Jie Zhang, Guoqing Ding
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Medicine Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950347725000143
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